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Without a much larger data set to establish kurtosis and skewness, I think the best course of action is just to assume that FFMIs are normally distributed. Ultimately, I think the entire notion of proposing a ‘limit’ is wrongheaded. Unless there is some physical law that imposes an unavoidable constraint to further growth (I’m not aware of one), the Law of Truly Large Numbers kicks in when you’re trying to see what’s possible for the best of the best in a massive population; the incredibly-unlikely-but-not-impossible becomes a near certitude until you reach something truly impossible. In this case, we simply don’t know where ‘impossible’ starts. Instead of looking for a limit, we should be more concerned with likelihood. This leads us to the next question: 2) If there’s not a hard limit that tells you someone is definitely on drugs, is there a way to assign a likelihood to someone being drug-free? Why, I’m glad you asked! Let’s bring back this chart: These are the odds that someone will fall within a given FFMI range with or without drugs. The higher the blue line is above the red line, the more likely someone with that FFMI is drug-free, and the higher the red line is above the blue line, the more likely it is that someone with that FFMI is on drugs. So, where the red line and the blue line intersect around 24, that means you have a roughly 50/50 chance that someone with that FFMI is drug-free. However, we can’t leave it there. If we did, we’d be guilty of base rate neglect. The likelihood that someone is on steroids in an entire population will also influence the odds of someone with a given FFMI being on drugs or not. Here’s a simple way to illustrate this: If 20% of people can reach an FFMI of 25 drug-free, and 60% of people can do it on drugs, then you’d assume that there was a 75% chance that someone with an FFMI of 25 was on drugs. However, if you’re dealing with a population of 4,000 lifters, 3,000 of whom are drug-free and 1,000 of whom are on steroids, then you’d expect 600 drug-free people to have an FFMI of 25 (3000*0. In other words, a random person with an FFMI of 25 in that population would have a 50% chance of being drug-free, even though the odds are dramatically higher for any single steroid-user to reach an FFMI of 25. If you reverse the scenario ‘ 3,000 users and 1,000 non-users ‘ then you’d be looking at 1,800 users with an FFMI of 25 and only 200 non-users with an FFMI of 25, making it an 89% that someone with an FFMI of 25 was on drugs. With that in mind, I made a handy dandy calculator incorporating the FFMI distributions of users and non-users and the percentage of a given population you think is truly drug-free. So, if you are curious about the status of a given bro in the gym, and you think 80% of gym-goers who actually populate the free-weight section are drug-free, you’d enter 0. 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