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More serious (though rare) side-effects can include impotence, asthma attack, memory loss or heart failure. A high-profile case of Beta Blocker use at the elite level was in 2008, when Olympic shooter Kim Jong-su tested positive for Propranolol and was subsequently stripped of his medals. Beta Blockers can be detected in human urine using Gas Chromatography Mass Spectrometry. Many sports will not allow the presence of Beta Blockers at any level, despite an athlete’s claims that it may have been used for a legitimate medical reason. A Gas Chromatography Mass Spectrometry machine. These machines can be used for urine testing. Image source: Polimerek / Wikimedia Commons. Diuretics work to promote the production of urine. While putting your hand up for a toilet break may not be deemed professional in modern sport, athletes use diuretics to assist with weight-loss (the loss of water through urination leads to an overall loss of body weight). This is particularly useful in sports where weight is critical such as boxing, rowing or horse-racing. An added benefit of all these toilet breaks is that other drugs present in the system could also more quickly be ‘flushed out’ of the body. The increased urine volume also aids in the dilution of doping agents and their metabolites. All classes of diuretics are considered to be ‘masking agents’ by WADA and are banned both in and out of competition. Diuretics have been banned in sport since 1988. There are more than 20 diuretics banned by the IOC and WADA. Some examples include: hydrochlorothiazide desmopressin probenecid amiloride metolazone. When used to treat legitimate medical conditions such as heart failure, high blood pressure, kidney and liver problems and glaucoma, and under the supervision of a trained doctor, diuretic use is quite safe, drostan-e 200 mg injectable steroids masteron. However, because diuretics promote frequent urination, when used without medical supervision they can lead to dehydration, dizziness, muscle cramps and constipation. Other side effects include tiredness, fever, skin rash and loss of appetite. More serious effect include disruptions to the normal rhythms of the heart, and electrolyte abnormalities, which can affect kidney function. Jamaica’s most successful female track athlete, Veronica Campbell-Brown, tested positive for a banned diuretic in 2013. Former Australian cricketer Shane Warne tested positive for a banned diuretic in 2003 and subsequently was suspended from all forms of cricket for 12 months, leading to him missing the 2003 ICC World Cup. Warne claimed to have taken the tablet to ‘get rid of a double chin’ for television appearances. Previously, diuretics were detected in biological samples through the use of high-performance liquid chromatography (HPLC) coupled with ultraviolet-diode array detection (UV-DAD). However, this method was not deemed rigorous enough in determining the unequivocal identification of banned substances. undefined
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